The Mercedes-Benz E-Class is often considered to be a comparable model to the Audi A6. Both are mid-size luxury saloons that offer a comfortable ride, advanced technology, and powerful engines. The Audi A6 is often praised for its understated, elegant design, while the Mercedes-Benz E-Class has a more dramatic and sportier look. Both cars are available with a range of engines, but the Mercedes-Benz E-Class may offer a bit more power and better acceleration than the Audi A6. The Audi A6, however, is often praised for its smooth, comfortable ride.